Most side-effects listed for statins are not caused by the drugs, according to a major review published in The Lancet. Researchers analysed 19 randomised trials involving 124,000 people followed for an average of four and a half years. The evidence supported only muscle pain, diabetes risk, and four minor effects, including liver test changes and tissue swelling. Researchers found no strong evidence linking statins to problems such as memory loss, depression, sleep issues, or nerve damage. The study shows that statins greatly reduce heart attacks and strokes, while the risk of harm remains low. Lead author Christina Reith said the benefits clearly outweigh the risks for most patients. Experts called for updated drug labels to reflect the evidence and help patients make informed decisions.
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